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Rohon-beard neurons do not succumb to programmed cell death during zebrafish development

Abstract: During neural development, sculpting of early formed circuits by cell death and synaptic pruning is necessary to generate a functional and efficient nervous system. This allows for the establishment of rudimentary circuits which necessitate early organism survival to later undergo subsequent refinement. These changes facilitate additional specificity to stimuli which can lead to increased behavioral complexity. 

Kendra E Liu, Sarah Kucenas