Antimalarial resistance risk in Mozambique detected by a novel quadruplex droplet digital PCR assay
Abstract
While the Plasmodium falciparum malaria parasite continues to cause severe disease globally, Mozambique is disproportionally represented in malaria case totals. Acquisition of copy number variations (CNVs) in the parasite genome contributes to antimalarial drug resistance through overexpression of drug targets. Read More
Noah Brown, Clemente da Silva, Caroline Webb, Daniela Matias, Brigite Dias, Beatriz Cancio, Miguel Silva, Ruben Viegas, Crizolgo Salvador, Nordino Chivale, Sonia Luis, Paulo Arnaldo, Julia Zulawinska, Christopher C Moore, Fatima Nogueira, Jennifer L Guler
https://pubmed.ncbi.nlm.nih.gov/38771031/