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Ariel Pani

Assistant Professor of Biology
Lab Website

Office Address: 310 PLSB

Education

B.A., Cornell University, College Scholar in Organismal Biology, 2004
Ph.D., The University of Chicago, Evolutionary Biology, 2013
Postdoctoral, University of North Carolina at Chapel Hill, 2013-2019

Recent Publications

Full Publication list can be found at https://www.ncbi.nlm.nih.gov/myncbi/ariel.pani.2/bibliography/public/

Gibney TV, Pani AM. Engineering the C. elegans genome with a nested, self-excising selection cassette. bioRxiv 2025.05.01.651742; doi: 10.1101/2025.05.01.651742

Gibney TV, Mardick JI, Rasmussen NR, Latifi L, Sundaram MV, Reiner DJ, Pani AM. FGF-dependent, polarized SOS activity orchestrates directed migration of C. elegans muscle progenitors independent of canonical effectors in vivobioRxiv 2025.04.11.648432; doi: 10.1101/2025.04.11.648432

Gibney TV, Pani AM. FGF diffusion is required for the directed migration of postembryonic muscle progenitors in C. elegansbioRxiv 2025.03.19.643693; doi: 10.1101/2025.03.19.643693

Pani AM (2024) Organogenesis: how active forces maintain integrity of migrating cells under pressure, Current Biology, 34(14):R693-R696, doi: 10.1016/j.cub.2024.06.019

Zimyanin V, Magaj M, Manzi NI, Yu C-H, Gibney T, Basaran M, Horton X, Pani AM, Needleman D, Dickinson DJ, Redemann S. Chromokinesin Klp-19 regulates microtubule overlap and dynamics during anaphase in C. elegansbioRxiv 2023.10.26.564275; doi: 10.1101/2023.10.26.564275

Gibney TV, Favichia M, Latifi L, Medwig-Kinney TN, Matus DQ, McIntyre DC, Arrigo AB, Branham KR, Bubrig LT, Ghaddar A, Jiranek JA, Liu KE, Marcucci CG, Porter RJ, Pani AM (2023) A simple method to dramatically increase C. elegans germline microinjection efficiency. Developmental Biology, Jul 9;S0012-1606(23)00129-X. doi: 10.1016/j.ydbio.2023.07.003

Medwig-Kinney TN, Kinney BA, Martinez MAQ, Yee C, Sirota SS, Mullarkey AA, Somineni N, Hippler J, Zhang W, Shen K, Hammell CM, Pani AM, Matus DQ (2023) Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. eleganseLife, 12:RP84355; doi: 10.7554/eLife.84355.3 

Andrade-Lopez JM, Pani AM, Wu M, Gerhart J, Lowe CJ (2023) Molecular characterization of nervous system organization in the hemichordate Saccoglossus kowalevskiiPLoS Biology, 21(9):e3002242, doi: 10.1371/journal.pbio.3002242

Pani AM, Favichia M, Goldstein B (2023) Long-distance Wnt transport in axons highlights cell type-specific modes of Wnt transport in vivobioRxiv 2023.05.03.539245; doi: 10.1101/2023.05.03.539245

Costa DS, Kenny-Ganzert IW, Chi Q, Kelley LC, Park K, Garde A, Matus DQ, Park S, Yogev S, Goldstein B, Gibney TV, Pani AM, Sherwood DR (2023) C. elegans anchor cell transcriptome: ribosome biogenesis and endomembrane expansion promote cell invasion. Development 150, dev201570; doi: 10.1242/dev.201570

Pani AM, Gibney TV, Medwig-Kinney TN, Matus DQ, Goldstein B (2022) A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegansmicroPublication Biology, doi: 10.17912/micropub.biology.000603

Medwig-Kinney TN, Sirota SS, Gibney TV, Pani AM, Matus DQ (2022) An in vivo toolkit to visualize endogenous LAG-2/Delta and LIN-12/Notch signaling in C. elegansmicroPublication Biology, doi: 10.17912/micropub.biology.000602

Lantzsch I, Yu CH, Yazdkhasti H, Lindow N, Szentgyorgyi E, Prohaska S, Pani AM, Srayko M, Furthauer S, Redemann S (2021) Microtubule reorganization during female meiosis in C. elegans. eLife, 10:e58903, doi: 10.7554/eLife.58903  

Adikes RC, Kohrman AQ, Martinez MAQ, Palmisano NJ, Smith JJ, Medwig-Kinney TN, Min M, Sallee MD, Ahmed OB, Kim N, Liu S, Morabito RD, Weeks N, Zhao Q, Zhang W, Feldman JL, Barkoulas M, Pani AM, Spencer SL, Martin BL, Matus DQ (2020) Visualizing the metazoan proliferation-quiescence decision in vivoeLife, 9:e63265, doi: 10.7554/eLife.63265

Gordon KL, Payne SG, Linden-High LM, Pani AM, Goldstein B, Hubbard JA, Sherwood DR. (2019) Ectopic germ cells can induce niche-like enwrapment by body wall muscle. Current Biology 29: 828-833.e5, doi: 10.1016/j.cub.2019.01.056

Pani AM, Goldstein B (2018) Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal. eLife 7:e38325 doi: 10.7554/eLife.38325

Heppert JK, Pani AM, Roberts AM, Dickinson DJ, Goldstein B (2018) A CRISPR tagging-based screen reveals localized players in Wnt-directed asymmetric cell division. Genetics 208: 1147-1164, doi: 10.1534/genetics.117.300487

Darras S, Fritzenwanker J, Uhlinger K, Farrelly E, Pani AM, Hurley I, Norris R, Osowitz M, Terasaki M, Wu M, Aronowicz J, Kirschner M, Gerhart J, Lowe CJ (2018) Anteroposterior patterning by early canonical Wnt signaling during hemichordate development. PLoS Biology 16: e2003698, doi: 10.1371/journal.pbio.2003698