Structural and functional damage to neuronal nuclei caused by extracellular tau oligomers

Abstract
Introduction: Neuronal nuclei are normally smoothly surfaced. In Alzheimer's disease (AD) and other tauopathies, though, they often develop invaginations. We investigated mechanisms and functional consequences of neuronal nuclear invagination in tauopathies.

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https://pubmed.ncbi.nlm.nih.gov/38069673/
Xuehan Sun, Guillermo Eastman, Yu Shi, Subhi Saibaba, Ana K Oliveira, John R Lukens, Andrés Norambuena, Joseph A Thompson, Michael D Purdy, Kelly Dryden, Evelyn Pardo, James W Mandell, George S Bloom