Structural and functional damage to neuronal nuclei caused by extracellular tau oligomers

Abstract
Introduction: Neuronal nuclei are normally smoothly surfaced. In Alzheimer's disease (AD) and other tauopathies, though, they often develop invaginations. We investigated mechanisms and functional consequences of neuronal nuclear invagination in tauopathies. Read More

https://pubmed.ncbi.nlm.nih.gov/38069673/
Xuehan Sun, Guillermo Eastman, Yu Shi, Subhi Saibaba, Ana K Oliveira, John R Lukens, Andrés Norambuena, Joseph A Thompson, Michael D Purdy, Kelly Dryden, Evelyn Pardo, James W Mandell, George S Bloom