Office Address: 404 PLSB
Lab: 434 982-5478

Education

B.S., Wuhan University, 1992
Ph.D., The Johns Hopkins University, 2000

Research Interests

We are interested in studying how microbes evolve, adapt and diversify at the molecular, organismal and community levels. To gain insights into the fundamental mechanisms underlying these processes, we use an interdisciplinary approach that draws upon the fields of genomics, evolutionary biology, computational biology, and ecology. In particular, a large portion of our work will employ phylogenomics -- the synergistic integration of evolutionary and genomic analyses -- to investigate these questions. Research opportunities are available.

See my lab homepage for details.

Representative Publications

Ren, T., Glatt, D.U., Nguyen, T.N., Allen, E.K., Early, S.V., Sale, M., Winther, B., Wu, M. 16S rRNA survey revealed complex bacterial communities and evidence of bacterial interference on human adenoids. Environmental Microbiology. (In press).

Kembel, S.W., Wu, M., Eisen, J.A., Green, J.L. Incorporating 16S gene copy number information improves estimates of microbial diversity and abundance. PLoS Computational Biology. (In press).

Kolling, G.L., Wu, M., Alcantara-Warren, C., Durmaz, E., Klaenhammer, T.R., Guerrant, R.L. (2012). Lactic acid production by Streptococcus thermophilus alters Clostridium difficile infection and in vitro Toxin A production. Gut Microbes, 3:6,1-7. doi:10.4161/gutmicrobes.21757.

Lu, H.P., Wang, Y.B., Huang, S.W., Lin, C.Y., Wu, M., Hsieh, C.H., Yu, H.T. (2012). Metagenomic analysis reveals a functional signature for biomass degradation by cecal microbiota in the leaf-eating flying squirrel (Petaurista alborufus lena). BMC Genomics, 13:466. doi:10.1186/1471-2164-13-466.

Kolling, G., Wu, M., Guerrant, R.L. (2012). Enteric Pathogens Through Life Stages. Frontiers in Cellular and Infection Microbiology, 2:114. doi:10.3389/fcimb.2012.00114.

Koeppel, A.F. and Wu, M. (2012). Lineage-dependent ecological coherence in bacteria. FEMS Microbiology Ecology, doi: 10.1111/j.1574-6941.2012.01387.x. Download 10.1111_j.1574-6941.2012.01387.x.pdf.

For a comprehensive list of Dr. Wu's publications, please click here.