Niche cells regulate primordial germ cell quiescence in response to basement membrane signaling
Stem cell quiescence, proliferation and differentiation are controlled by interactions with niche cells and a specialized extracellular matrix called basement membrane (BM). Direct interactions with adjacent BM are known to regulate stem cell quiescence; however, it is less clear how niche BM relays signals to stem cells that it does not contact. Click here, to read full publication.
Daniel C McIntyre, Jeremy Nance